Jacek Kleszczyński¹, Iryna Boliukh², Agnieszka Rombel-Bryzek², Rafał J. Bułdak²

¹Emergency Department, Institute of Medical Sciences, University of Opole, Opole, Poland.

²Department of Clinical Biochemistry and Laboratory Diagnostics, Institute of Medical Sciences, University of Opole, Opole, Poland.

Corresponding Author’s information: Jacek Kleszczyński, Emergency Department, Institute of Medical Sciences, University of Opole, Oleska 48, 45052 Opole.

Citation: Jacek Kleszczyński, Iryna Boliukh, Agnieszka Rombel-Bryzek, Rafał J. Bułdak (2025). Severe Hyperglycaemia with Concomitant Asymptomatic COVID-19 Infection: A Case Report Severe Hyperglycaemia with Concominant COVID-19. American J Case Rep Clin Imag. 2025; September, 2(2),1-3.

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Abstract:

Background: Acute hyperglycaemic crises, such as diabetic ketoacidosis (DKA) and hyperosmolar hyperglycaemic state (HHS), are serious and potentially life-threatening complications of diabetes that can also be triggered by viral infections.

Case Report: A 64-year-old woman was admitted to the hospital emergency department because of syncope and impaired consciousness that began the previous day. The patient had experienced polydipsia, polyuria, and weight loss over the past four weeks. Laboratory results revealed a serum glucose concentration of 2362.2 mg/dL. A positive RT-PCR test for SARS-CoV-2 was also documented. Finally, the patient was diagnosed with hyperglycaemic-hyperosmolar syndrome (HHS), hypokalaemia and nonketotic metabolic acidosis. Hyperglycaemia was treated with an insulin bolus, followed by continuous infusion under glucose monitoring. The patient received also multi-electrolyte solution therapy.

Conclusion: COVID-19 infection may significantly influence blood glucose levels. During the diagnostic evaluation and treatment of hyperglyceridaemia, clinicians should remain vigilant for the potential diagnosis of DKA and/or HHS.